Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were synthesised and characterised by FT-IR, 13C NMR, 1H NMR, LC-MS and elemental analysis. Their inhibitory effect on AChE, and carbonic anhydrase I and II...

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Bibliographic Details
Main Authors: Mustafa Durgun, Cüneyt Türkeş, Mesut Işık, Yeliz Demir, Ali Saklı, Ali Kuru, Abdussamat Güzel, Şükrü Beydemir, Suleyman Akocak, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
acetylcholinesterase
carbonic anhydrase
synthesis
sulphonamide
molecular docking
Online Access:http://dx.doi.org/10.1080/14756366.2020.1746784

Internet

http://dx.doi.org/10.1080/14756366.2020.1746784

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