Piceatannol and its analogues alleviate Staphylococcus aureus pathogenesis by targeting β-lactamase biofilms and α-hemolysin

Piceatannol and its analogues alleviate Staphylococcus aureus pathogenesis by targeting β-lactamase biofilms and α-hemolysin

Abstract β-Lactamases, biofilms and toxins pose challenges for combating S. aureus infection. Thus, identifying inhibitors that can restore bacterial sensitivity to antibiotics, destroy biofilms, and antitoxins is a promising way to develop alternative agents. In this study, we found that piceatanno...

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Bibliographic Details
Main Authors: Guizhen Wang, Jingyao Wen, Zizeng Tian, Hanbing Zhou, Xinli Peng, Peigang Zhang, Zhandong Li
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Staphylococcus aureus
Biofilm
β-lactamase
α-hemolysin
Anti-infection
Online Access:https://doi.org/10.1038/s41598-025-89654-1

Internet

https://doi.org/10.1038/s41598-025-89654-1

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