Extended Work Function Shift of Large‐Area Biofunctionalized Surfaces Triggered by a Few Single‐Molecule Affinity Binding Events

Extended Work Function Shift of Large‐Area Biofunctionalized Surfaces Triggered by a Few Single‐Molecule Affinity Binding Events

Abstract Few binding events are here shown to elicit an extended work function change in a large‐area Au‐surface biofunctionalized with ≈108 capturing antibodies. This is demonstrated by Kelvin probe force microscopy (KPFM), imaging a ≈105 µm2 wide Au‐electrodes covered by a dense layer (≈104 µm−2)...

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Bibliographic Details
Main Authors: Cinzia Di Franco, Eleonora Macchia, Lucia Sarcina, Nicoletta Ditaranto, Aniqa Khaliq, Luisa Torsi, Gaetano Scamarcio
Format: Article
Language:English
Published: Wiley-VCH 2023-02-01
Series:Advanced Materials Interfaces
Subjects:
atomic force microscopy
biofunctionalized surfaces
electrolyte gated transistors
Kelvin probe force microscopy
surface potential imaging single‐molecule sensors
Online Access:https://doi.org/10.1002/admi.202201829

Internet

https://doi.org/10.1002/admi.202201829

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