Adapter-Mediated Transduction with Lentiviral Vectors: A Novel Tool for Cell-Type-Specific Gene Transfer

Adapter-Mediated Transduction with Lentiviral Vectors: A Novel Tool for Cell-Type-Specific Gene Transfer

Selective gene delivery to a cell type of interest utilizing targeted lentiviral vectors (LVs) is an efficient and safe strategy for cell and gene therapy applications, including chimeric antigen receptor (CAR)-T cell therapy. LVs pseudotyped with measles virus envelope proteins (MV-LVs) have been r...

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Bibliographic Details
Main Authors: Nicole Cordes, Nora Winter, Carolin Kolbe, Bettina Kotter, Joerg Mittelstaet, Mario Assenmacher, Toni Cathomen, Andrew Kaiser, Thomas Schaser
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
lentiviral vectors
gene therapy
CAR-T cells
immunotherapy
Online Access:https://www.mdpi.com/1999-4915/14/10/2157

Internet

https://www.mdpi.com/1999-4915/14/10/2157

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