The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture

The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture

A better understanding of HIV-1 latency is a research priority in HIV cure research. Conversely, little is known about the latency characteristics of HIV-2, the closely related human lentivirus. Though both viruses cause AIDS, HIV-2 infection progresses more slowly with significantly lower viral loa...

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Bibliographic Details
Main Authors: Anne Bruggemans, Gerlinde Vansant, Paulien Van de Velde, Zeger Debyser
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Virus Eradication
Subjects:
HIV-1
HIV-2
Latency
Integration
Reactivation
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664023000298

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http://www.sciencedirect.com/science/article/pii/S2055664023000298

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