High-throughput segmentation of unmyelinated axons by deep learning

Abstract Axonal characterizations of connectomes in healthy and disease phenotypes are surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of fibers in the nervous system, have largely been ignored as their quantitative assessment quickly becomes unmanageable as th...

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Bibliographic Details
Main Authors: Emanuele Plebani, Natalia P. Biscola, Leif A. Havton, Bartek Rajwa, Abida Sanjana Shemonti, Deborah Jaffey, Terry Powley, Janet R. Keast, Kun-Han Lu, M. Murat Dundar
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-04854-3