Optoplasmonic characterisation of reversible disulfide interactions at single thiol sites in the attomolar regime
Visualising single-molecule reactions, to understand their mechanisms, is a challenging task. Here, the authors investigate disulfide exchange reactions with thiolates immobilised on a gold nanoparticle through a label-free optoplasmonic sensor, and detect individual disulfide interactions in soluti...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-15822-8 |