Three Decades of Research on O-GlcNAcylation – A Major Nutrient Sensor that Regulates Signaling, Transcription and Cellular Metabolism.
Even though the dynamic modification of polypeptides by the monosaccharide, O-linked N-acetylglucosamine (O-GlcNAcylation) was discovered over thirty-years ago, its physiological significance as a major nutrient sensor that regulates myriad cellular processes has only recently been more widely appre...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-10-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00183/full |