STATs in Lung Development: Distinct Early and Late Expression, Growth Modulation and Signaling Dysregulation in Congenital Diaphragmatic Hernia

STATs in Lung Development: Distinct Early and Late Expression, Growth Modulation and Signaling Dysregulation in Congenital Diaphragmatic Hernia

Background: Congenital diaphragmatic hernia (CDH) is a life-threatening developmental anomaly, intrinsically combining severe pulmonary hypoplasia and hypertension. During development, signal transducers and activators of transcription (STAT) are utilized to elicit cell growth, differentiation, and...

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Bibliographic Details
Main Authors: Paulina Piairo, Rute S. Moura, Maria João Baptista, Jorge Correia-Pinto, Cristina Nogueira-Silva
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Signal transducer and activator of transcription (STAT)
Suppressor of cytokine signaling (SOCS)
Congenital diaphragmatic hernia (CDH)
Lung development
Nitrofen
Online Access:https://www.karger.com/Article/FullText/486218

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https://www.karger.com/Article/FullText/486218

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