Immunotherapy With 5, 15-DPP Mediates Macrophage M1 Polarization and Modulates Subsequent Mycobacterium tuberculosis Infectivity in rBCG30 Immunized Mice

Immunotherapy With 5, 15-DPP Mediates Macrophage M1 Polarization and Modulates Subsequent Mycobacterium tuberculosis Infectivity in rBCG30 Immunized Mice

Tuberculosis (TB) is a significant and continuing problem worldwide, with a death toll of around 1.5 million human lives annually. BCG, the only vaccine against TB, offers a varied degree of protection among human subjects in different regions and races of the world. The majority of the population l...

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Bibliographic Details
Main Authors: Faraz Ahmad, Mohd. Saad Umar, Nazoora Khan, Fauzia Jamal, Pushpa Gupta, Swaleha Zubair, Umesh Datta Gupta, Mohammad Owais
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
vaccine
immunotherapeutics
IL-10 (interleukin 10)
5
15-diphenylporphyrin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.706727/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.706727/full

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