A Single Vaccination of Chimeric Bivalent Virus-Like Particle Vaccine Confers Protection Against H9N2 and H3N2 Avian Influenza in Commercial Broilers and Allows a Strategy of Differentiating Infected from Vaccinated Animals

A Single Vaccination of Chimeric Bivalent Virus-Like Particle Vaccine Confers Protection Against H9N2 and H3N2 Avian Influenza in Commercial Broilers and Allows a Strategy of Differentiating Infected from Vaccinated Animals

H9N2 and H3N2 are the two most important subtypes of low pathogenic avian influenza viruses (LPAIV) because of their ongoing threat to the global poultry industry and public health. Although commercially available inactivated H9N2 vaccines are widely used in the affected countries, endemic H9N2 avia...

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Bibliographic Details
Main Authors: Yi-xue Sun, Zheng-rong Li, Peng-ju Zhang, Jin-hong Han, Hai-yang Di, Jia-yi Qin, Yan-long Cong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
influenza virus
H9N2 and H3N2 subtypes
VLP
chimeric vaccine
DIVA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.902515/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.902515/full

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