Dysregulated miRNA and mRNA Expression Affect Overlapping Pathways in a Huntington’s Disease Model

Dysregulated miRNA and mRNA Expression Affect Overlapping Pathways in a Huntington’s Disease Model

Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in the Huntingtin gene. Transcriptional dysregulation is one of the main cellular processes affected by mutant Huntingtin (mHtt). In this study, we investigate the alterations in miR...

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Bibliographic Details
Main Authors: Nóra Zsindely, Gábor Nagy, Fruzsina Siági, Anita Farkas, László Bodai
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
Huntington’s disease
neurodegeneration
miRNA
transcriptomics
transcription
<i>Drosophila</i>
Online Access:https://www.mdpi.com/1422-0067/24/15/11942

Internet

https://www.mdpi.com/1422-0067/24/15/11942

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