DNA methylation profiles in sibling pairs discordant for intrauterine exposure to maternal gestational diabetes

DNA methylation profiles in sibling pairs discordant for intrauterine exposure to maternal gestational diabetes

Intrauterine exposure to hyperglycemia is reported to confer increased metabolic risk in later life, supporting the ‘developmental origins of health and disease’ hypothesis. Epigenetic alterations are suggested as one of the possible underlying mechanisms. In this study, we compared pairwise DNA met...

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Bibliographic Details
Main Authors: Eunae Kim, Soo Heon Kwak, Hye Rim Chung, Jung Hun Ohn, Jae Hyun Bae, Sung Hee Choi, Kyong Soo Park, Joon-Seok Hong, Joohon Sung, Hak Chul Jang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-10-01
Series:Epigenetics
Subjects:
dna methylation
epigenome-wide association study
gestational diabetes mellitus
siblings
intrauterine environment
Online Access:http://dx.doi.org/10.1080/15592294.2017.1370172

Internet

http://dx.doi.org/10.1080/15592294.2017.1370172

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