Angelica sinensis polysaccharides alleviate the oxidative burden on hematopoietic cells by restoring 5-fluorouracil-induced oxidative damage in perivascular mesenchymal progenitor cells

Angelica sinensis polysaccharides alleviate the oxidative burden on hematopoietic cells by restoring 5-fluorouracil-induced oxidative damage in perivascular mesenchymal progenitor cells

AbstractContext 5-Fluorouracil (5-FU)-injured stromal cells may cause chronic bone marrow suppression; however, the underlying mechanism remains unclear. Angelica sinensis polysaccharide (ASP), the main biologically active ingredient of the Chinese herb, Angelica sinensis (Oliv.) Diels (Apiaceae), m...

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Bibliographic Details
Main Authors: Yilin Niu, Hanxianzhi Xiao, Biyao Wang, Ziling Wang, Kunhang Du, Yaping Wang, Lu Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Pharmaceutical Biology
Subjects:
Hematopoietic niche
oxidative stress
premature senescence of hematopoietic cells
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2023.2207592

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2023.2207592

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