An UHPLC-MS/MS method for quantification of the CDK4/6 inhibitor abemaciclib in human serum

Background: Abemaciclib is a new oral targeted treatment option for patients with advanced breast cancer. The emerging field of oral antitumor therapeutics presents challenges for both patients and healthcare teams; non-adherence and high inter-individual pharmacokinetic variability can influence re...

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Bibliographic Details
Main Authors: Katharina Habler, Michael Vogeser, Daniel Teupser
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X22000025