Association of Maternal Immunity with Rotavirus Vaccine Immunogenicity in Zambian Infants.

INTRODUCTION:Live attenuated oral vaccines against rotavirus (RV) have been shown to be less efficacious in children from developing countries. Reasons for this disparity are not fully understood. We assessed the role of maternal factors including breast milk RV-specific IgA, transplacentally acquir...

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Bibliographic Details
Main Authors: Roma Chilengi, Michelo Simuyandi, Lauren Beach, Katayi Mwila, Sylvia Becker-Dreps, Devy M Emperador, Daniel E Velasquez, Samuel Bosomprah, Baoming Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4790930?pdf=render