Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells
Abstract Background The non-catalytic region of tyrosine kinase (Nck) is an adaptor protein, which is ubiquitously expressed in many types of cells. In T cells, the Nck1 isoform promotes T cell receptor signalling as well as actin polymerisation. However, the role of Nck1 in the lipid metabolism in...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-07-01
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Series: | BMC Molecular and Cell Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12860-022-00436-3 |