Sedative–hypnotic effect of YZG-330 and its effect on chloride influx in mouse brain cortical cells

Sedative–hypnotic effect of YZG-330 and its effect on chloride influx in mouse brain cortical cells

This study was to examine the sedative–hypnotic effect of YZG-330 and its influence on Cl− influx in mouse cortical cells. In a sleep time-prolongation test in which mice were administered a threshold dosage of sodium pentobarbital (ip), YZG-330 (0.125, 0.5 and 2 mg/kg, po) prolonged the sleep time...

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Bibliographic Details
Main Authors: Lili Liu, Shaobo Jia, Jingwen Dong, Ying Zhang, Ruiming Xu, Jianjun Zhang
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Sedative–hypnotic
Sleep
Cl− influx
MQAE
Cortical cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383513000634

Internet

http://www.sciencedirect.com/science/article/pii/S2211383513000634

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