Quantum dots for tracking dendritic cells and priming an immune response in vitro and in vivo.

Dendritic cells (DCs) play a key role in initiating adaptive immune response by presenting antigen to T cells in lymphoid organs. Here, we investigate the potential of quantum dots (QDs) as fluorescent nanoparticles for in vitro and in vivo imaging of DCs, and as a particle-based antigen-delivery sy...

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Bibliographic Details
Main Authors: Debasish Sen, Thomas J Deerinck, Mark H Ellisman, Ian Parker, Michael D Cahalan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2538605?pdf=render