The <named-content content-type="genus-species">Mus musculus</named-content> Papillomavirus Type 1 E7 Protein Binds to the Retinoblastoma Tumor Suppressor: Implications for Viral Pathogenesis

The <named-content content-type="genus-species">Mus musculus</named-content> Papillomavirus Type 1 E7 Protein Binds to the Retinoblastoma Tumor Suppressor: Implications for Viral Pathogenesis

ABSTRACT The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous cell carcinomas in laboratory mice. T...

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Bibliographic Details
Main Authors: Tao Wei, Miranda Grace, Aayushi Uberoi, James C. Romero-Masters, Denis Lee, Paul F. Lambert, Karl Munger
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mBio
Subjects:
papillomavirus
viral pathogenesis
retinoblastoma tumor suppressor
E7
MmuPV1
host-pathogen interactions
Online Access:https://journals.asm.org/doi/10.1128/mBio.02277-21

Internet

https://journals.asm.org/doi/10.1128/mBio.02277-21

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