Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19

Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19

Abstract Background Coronavirus disease 2019 (COVID-19) patients can develop pulmonary fibrosis (PF), which is associated with impaired outcome. We assessed specific leukocytic transcriptome profiles associated with PF and the influence of early dexamethasone (DEXA) treatment on the clinical course...

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Bibliographic Details
Main Authors: Emma J. Kooistra, Kilian Dahm, Antonius E. van Herwaarden, Jelle Gerretsen, Melanie Nuesch Germano, Karoline Mauer, Ruben L. Smeets, Sjef van der Velde, Maarten J. W. van den Berg, Johannes G. van der Hoeven, Anna C. Aschenbrenner, Joachim L. Schultze, Thomas Ulas, Matthijs Kox, Peter Pickkers
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Respiratory Research
Subjects:
Acute respiratory distress syndrome
Coronavirus disease 2019
Dexamethasone
Pulmonary fibrosis
Transcriptomics
Online Access:https://doi.org/10.1186/s12931-023-02496-1

Internet

https://doi.org/10.1186/s12931-023-02496-1

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