Identification of a carbohydrate recognition motif of purinergic receptors

As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs). Here, we employed P2Y purinoceptor 14 (P2Y14), a drug...

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Bibliographic Details
Main Authors: Lifen Zhao, Fangyu Wei, Xinheng He, Antao Dai, Dehua Yang, Hualiang Jiang, Liuqing Wen, Xi Cheng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/85449