Design of Specific and Efficient sgRNA for CRISPR/Cas9 System to Knockout Superoxide Dismutase 2 in Breast Cancer Stem Cells

Design of Specific and Efficient sgRNA for CRISPR/Cas9 System to Knockout Superoxide Dismutase 2 in Breast Cancer Stem Cells

This study aimed to design specific and efficient single guide RNA (sgRNA) for CRISPR/Cas9 system to knockout human superoxide dismutase 2 (SOD2) in human breast cancer stem cells (BCSCs). To achieve this, two sgRNA targets were selected, located within the Ala16Val polymorphism and the conserved...

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Bibliographic Details
Main Authors: Sekar Arumsari, Septelia Inawati Wanandi, Resda Akhra Syahrani, Yukihide Watanabe, Seiya Mizuno
Format: Article
Language:English
Published: Universitas Indonesia 2024-02-01
Series:International Journal of Technology
Subjects:
breast cancer
crispr/cas9
sgrna
sod2
stem cells
Online Access:https://ijtech.eng.ui.ac.id/article/view/6680

Internet

https://ijtech.eng.ui.ac.id/article/view/6680

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