Differences in the microbiome of the small intestine of Leghorn lines divergently selected for antibody titer to sheep erythrocytes suggest roles for commensals in host humoral response

Differences in the microbiome of the small intestine of Leghorn lines divergently selected for antibody titer to sheep erythrocytes suggest roles for commensals in host humoral response

For forty generations, two lines of White Leghorn chickens have been selected for high (HAS) or low (LAS) antibody response to a low dose injection of sheep red blood cells (SRBCs). Their gut is home to billons of microorganisms and the largest number of immune cells in the body; therefore, the obje...

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Bibliographic Details
Main Authors: Shelly J. Nolin, Paul B. Siegel, Christopher M. Ashwell
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Physiology
Subjects:
microbiome
antibody response
VA tech HAS and LAS
machine learning
immunogenetics
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1304051/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1304051/full

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