How AlphaFold2 shaped the structural coverage of the human transmembrane proteome

Abstract AlphaFold2 (AF2) provides a 3D structure for every known or predicted protein, opening up new prospects for virtually every field in structural biology. However, working with transmembrane protein molecules pose a notorious challenge for scientists, resulting in a limited number of experime...

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Bibliographic Details
Main Authors: Márton A. Jambrich, Gabor E. Tusnady, Laszlo Dobson
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47204-7