Correlated mutations via regularized multinomial regression

<p>Abstract</p> <p>Background</p> <p>In addition to sequence conservation, protein multiple sequence alignments contain evolutionary signal in the form of correlated variation among amino acid positions. This signal indicates positions in the sequence that influence eac...

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Bibliographic Details
Main Authors: Sreekumar Janardanan, ter Braak Cajo JF, van Ham Roeland CHJ, van Dijk Aalt DJ
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/444