Sensitive universal detection of blood parasites by selective pathogen-DNA enrichment and deep amplicon sequencing

Sensitive universal detection of blood parasites by selective pathogen-DNA enrichment and deep amplicon sequencing

Abstract Background Targeted amplicon deep sequencing (TADS) has enabled characterization of diverse bacterial communities, yet the application of TADS to communities of parasites has been relatively slow to advance. The greatest obstacle to this has been the genetic diversity of parasitic agents, w...

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Bibliographic Details
Main Authors: Briana R. Flaherty, Joel Barratt, Meredith Lane, Eldin Talundzic, Richard S. Bradbury
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Microbiome
Subjects:
Molecular parasitology
Amplicon sequencing
Blood microbiota
Parasite biodiversity
Parasite detection
Molecular diagnosis
Online Access:https://doi.org/10.1186/s40168-020-00939-1

Internet

https://doi.org/10.1186/s40168-020-00939-1

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