Application of an Ultrasensitive NGS-Based Blood Test for the Diagnosis of Early-Stage Lung Cancer: Sensitivity, a Hurdle Still Difficult to Overcome

Application of an Ultrasensitive NGS-Based Blood Test for the Diagnosis of Early-Stage Lung Cancer: Sensitivity, a Hurdle Still Difficult to Overcome

Diagnosis of lung cancer requires histological examination of a tissue sample, which in turn requires an invasive procedure that cannot always be obtained. Circulating tumor DNA can be reliably detected in blood samples of advanced-stage lung cancer patients and might also be a minimally invasive al...

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Bibliographic Details
Main Authors: Malaïka Van der Linden, Bram Van Gaever, Lennart Raman, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Yolande Lievens, Liesbeth Ferdinande, Franceska Dedeurwaerdere, Joni Van der Meulen, Kathleen Claes, Björn Menten, Jo Van Dorpe
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
early-stage non-small cell lung cancer
liquid biopsy
cell-free DNA
circulating tumor DNA
next-generation sequencing
somatic mutations
Online Access:https://www.mdpi.com/2072-6694/14/8/2031

Internet

https://www.mdpi.com/2072-6694/14/8/2031

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