Monitoring and responding to signals of suicidal ideation in pragmatic clinical trials: Lessons from the GRACE trial for Chronic Sickle Cell Disease Pain

Monitoring and responding to signals of suicidal ideation in pragmatic clinical trials: Lessons from the GRACE trial for Chronic Sickle Cell Disease Pain

Sickle cell disease (SCD) is a hemoglobin disorder and the most common genetic disorder that affects 100,000 Americans and millions worldwide. Adults living with SCD have pain so severe that it often requires opioids to keep it in control. Depression is a major global public health concern associate...

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Bibliographic Details
Main Authors: Eric S. Swirsky, Andrew D. Boyd, Carol Gu, Larisa A. Burke, Ardith Z. Doorenbos, Miriam O. Ezenwa, Mitchell R. Knisely, Jonathan W. Leigh, Hongjin Li, Molly W. Mandernach, Robert E. Molokie, Crystal L. Patil, Alana D. Steffen, Nirmish Shah, Victoria A. deMartelly, Karen L. Staman, Judith M. Schlaeger
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Contemporary Clinical Trials Communications
Subjects:
Depression
Patient-reported outcomes
Research ethics
Suicidal ideation
Suicidal monitoring
Pragmatic trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865423001643

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http://www.sciencedirect.com/science/article/pii/S2451865423001643

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