Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

Abstract The current obesity epidemic and high prevalence of metabolic diseases necessitate efficacious and safe treatments. Brown adipose tissue in this context is a promising target with the potential to increase energy expenditure, however no pharmacological treatments activating brown adipose ti...

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Bibliographic Details
Main Authors: Vissarion Efthymiou, Lianggong Ding, Miroslav Balaz, Wenfei Sun, Lucia Balazova, Leon G. Straub, Hua Dong, Eric Simon, Adhideb Ghosh, Aliki Perdikari, Svenja Keller, Umesh Ghoshdastider, Carla Horvath, Caroline Moser, Bradford Hamilton, Heike Neubauer, Christian Wolfrum
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39715-8

Internet

https://doi.org/10.1038/s41467-023-39715-8

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