No Protective Effects of Hair Cells or Supporting Cells in Ototoxically Deafened Guinea Pigs upon Administration of BDNF

We investigated whether treatment with brain-derived neurotrophic factor (BDNF), which is known to protect spiral ganglion cells (SGCs), could also protect hair cells (HCs) and supporting cells (SCs) in the organ of Corti of a guinea pig model of sensorineural hearing loss. Hearing loss was induced...

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Bibliographic Details
Main Authors: Annamaria Tisi, Jochebed Rovers, Henk A. Vink, Dyan Ramekers, Rita Maccarone, Huib Versnel
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/12/1/2