GABA<sub>A</sub> and GABA<sub>B</sub> Receptors Mediate GABA-Induced Intracellular Ca<sup>2+</sup> Signals in Human Brain Microvascular Endothelial Cells

GABA<sub>A</sub> and GABA<sub>B</sub> Receptors Mediate GABA-Induced Intracellular Ca<sup>2+</sup> Signals in Human Brain Microvascular Endothelial Cells

Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by activating the ionotropic GABA<sub>A</sub> receptors on cerebrovascular endothelial cells, whereas the endothelial...

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Bibliographic Details
Main Authors: Sharon Negri, Francesca Scolari, Mauro Vismara, Valentina Brunetti, Pawan Faris, Giulia Terribile, Giulio Sancini, Roberto Berra-Romani, Francesco Moccia
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
hCMEC/D3 cells
GABA
GABA<sub>A</sub> receptors
GABA<sub>B</sub> receptors
Ca<sup>2+</sup> signaling
InsP<sub>3</sub> receptors
Online Access:https://www.mdpi.com/2073-4409/11/23/3860

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https://www.mdpi.com/2073-4409/11/23/3860

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