Sulindac derivatives inhibit cell growth and induce apoptosis in primary cells from malignant peripheral nerve sheath tumors of NF1-patients

<p>Abstract</p> <p>Background</p> <p>Malignant peripheral nerve sheath tumors (MPNSTs) are neoplasms leading to death in most cases. Patients with Neurofibromatosis type 1 have an increased risk of developing this malignancy. The metabolites of the inactive prodrug Suli...

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Bibliographic Details
Main Authors: Friedrich Reinhard E, Farassati Faris, Kluwe Lan, Kurtz Andreas, Frahm Silke, Mautner Victor F
Format: Article
Language:English
Published: BMC 2004-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/4/1/4