A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardiac function of low-dose rapamycin in 17 healthy client-owned dogs
Introduction:Geroscience studies of low-dose rapamycin in laboratory species have identified numerous benefits, including reversing age-related cardiac dysfunction. Cardiovascular benefits have been observed in dogs with 10 weeks of treatment, raising questions about possible benefits and adverse ef...
Main Authors: | Brian G. Barnett, Sonya R. Wesselowski, Sonya G. Gordon, Ashley B. Saunders, Daniel E. L. Promislow, Stephen M. Schwartz, Lucy Chou, Jeremy B. Evans, Matt Kaeberlein, Kate E. Creevy |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
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Series: | Frontiers in Veterinary Science |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1168711/full |
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