T‐cell lymphoma, B‐cell lymphoma, and myelodysplastic syndrome harboring common mutations: Trilineage tumorigenesis from a common founder clone

T‐cell lymphoma, B‐cell lymphoma, and myelodysplastic syndrome harboring common mutations: Trilineage tumorigenesis from a common founder clone

Abstract A 64‐year‐old man with angioimmunoblastic T‐cell lymphoma (AITL) subsequently developed diffuse large B‐cell lymphoma (DLBCL) and myelodysplastic syndrome (MDS). Genomic profiling of AITL, DLBCL, and MDS samples revealed that the tumor cells from all samples shared common mutations in TET2...

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Bibliographic Details
Main Authors: Kyoko Yoshihara, Yasuhito Nannya, Ikuo Matsuda, Mami Samori, Nobuto Utsunomiya, Masaya Okada, Seiichi Hirota, Seishi Ogawa, Satoshi Yoshihara
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:eJHaem
Subjects:
angioimmunoblastic T‐cell lymphoma
common mutations
diffuse large B‐cell lymphoma
founder clone
multilineage tumorigenesis
myelodysplastic syndrome
Online Access:https://doi.org/10.1002/jha2.354

Internet

https://doi.org/10.1002/jha2.354

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