GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells

Summary: Metabolism plays a crucial role in B cell differentiation and function. GSDMA3 is related to mitochondrial metabolism and is involved in immune responses. Here, we used Gsdma3 KO mice to examine the effect of GSDMA3 on B cells. The results demonstrated that GSDMA3 deficiency reprogrammed B...

Full description

Bibliographic Details
Main Authors: Fei Guan, Xi Luo, Ju Liu, Yanmei Huang, Qi Liu, Jiang Chang, Guofeng Fang, Danqing Kang, Heng Gu, Li Luo, Lu Yang, Zhaoyu Lin, Xiang Gao, Chaohong Liu, Jiahui Lei
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014189