Genipin-crosslinked fibrin hydrogels as a potential adhesive to augment intervertebral disc annulus repair

Treatment of damaged intervertebral discs is a significant clinical problem and, despite advances in the repair and replacement of the nucleus pulposus, there are few effective strategies to restore defects in the annulus fibrosus. An annular repair material should meet three specifications: have a...

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Bibliographic Details
Main Authors: RM Schek, AJ Michalek, JC Iatridis
Format: Article
Language:English
Published: Forum Multimedia Publishing LLC 2011-04-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol021/pdf/v021a28.pdf