Lung Organotypic Slices Enable Rapid Quantification of Acute Radiotherapy Induced Toxicity

Lung Organotypic Slices Enable Rapid Quantification of Acute Radiotherapy Induced Toxicity

To rapidly assess healthy tissue toxicities induced by new anti-cancer therapies (i.e., radiation alone or in combination with drugs), there is a critical need for relevant and easy-to-use models. Consistent with the ethical desire to reduce the use of animals in medical research, we propose to moni...

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Bibliographic Details
Main Authors: Maxime Dubail, Sophie Heinrich, Lucie Portier, Jessica Bastian, Lucia Giuliano, Lilia Aggar, Nathalie Berthault, José-Arturo Londoño-Vallejo, Marta Vilalta, Gael Boivin, Ricky A. Sharma, Marie Dutreix, Charles Fouillade
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
radiation toxicity
FLASH radiotherapy
organotypic lung slices
ex vivo model
combined treatment
Online Access:https://www.mdpi.com/2073-4409/12/20/2435

Internet

https://www.mdpi.com/2073-4409/12/20/2435

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