Familial/Bilateral and Sporadic Testicular Germ Cell Tumors Show Frequent Genetic Changes at Loci with Suggestive Linkage Evidence

Familial/Bilateral and Sporadic Testicular Germ Cell Tumors Show Frequent Genetic Changes at Loci with Suggestive Linkage Evidence

Testicular germ cell tumor (TGCT) is the most common tumor type among adolescent and young adult males. Familial clustering and bilateral disease are suggestive of a genetic predisposition among a subgroup of these patients, but susceptibility genes for testicular cancer have not yet been identified...

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Bibliographic Details
Main Authors: Rolf I. Skotheim, Sigrid M. Kraggerud, Sophie D. Fosså, Anna E. Stenwig, Tobias Gedde-Dahl, jr., Håvard E. Danielsen, Kjetill S. Jakobsen, Ragnhild A. Lothe
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
allelic imbalance
familial cancer
loss of heterozygosity
susceptibility gene
testicular germ cell tumor
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800439

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http://www.sciencedirect.com/science/article/pii/S1476558601800439

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