Translated Mutant <i>DSPP</i> mRNA Expression Level Impacts the Severity of Dentin Defects

Translated Mutant <i>DSPP</i> mRNA Expression Level Impacts the Severity of Dentin Defects

Hereditary dentin defects are conventionally classified into three types of dentinogenesis imperfecta (DGI) and two types of dentin dysplasia (DD). Mutations in the dentin sialophosphoprotein (<i>DSPP</i>) gene have been identified to cause DGI type II and III and DD type II; therefore,...

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Bibliographic Details
Main Authors: Youn Jung Kim, Yejin Lee, Hong Zhang, Figen Seymen, Mine Koruyucu, Sule Bayrak, Nuray Tuloglu, James P. Simmer, Jan C.-C. Hu, Jung-Wook Kim
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Personalized Medicine
Subjects:
hereditary
splicing mutation
dentinogenesis imperfecta
dentin sialophosphoprotein
<i>DSPP</i>
silent mutation
Online Access:https://www.mdpi.com/2075-4426/12/6/1002

Internet

https://www.mdpi.com/2075-4426/12/6/1002

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