Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis

Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis

Abstract Objective The objective was to determine if dose reduction is non-inferior to full-dose TNFi to maintain low disease activity (LDA) in patients already in remission with TNFi, in axial spondyloarthritis. Methods Randomized, parallel, non-inferiority, open-label multicentre clinical trial. P...

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Bibliographic Details
Main Authors: Jordi Gratacós, Caridad Pontes, Xavier Juanola, Jesús Sanz, Ferran Torres, Cristina Avendaño, Antoni Vallano, Gonzalo Calvo, Eugenio de Miguel, Raimon Sanmartí, The REDES-TNF investigators
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Arthritis Research & Therapy
Subjects:
Spondyloarthritis
Dose-tapering
Non-inferiority
TNF inhibitors
Online Access:http://link.springer.com/article/10.1186/s13075-018-1772-z

Internet

http://link.springer.com/article/10.1186/s13075-018-1772-z

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