Association of HLA-class II alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population

Association of HLA-class II alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population

BackgroundDisease relapse remains a major problem in the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In European populations, HLA-DPB1*04:01 is associated with both susceptibility and relapse risk in proteinase 3-ANCA positive AAV. In a Japanese population,...

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Main Authors: Aya Kawasaki, Ken-ei Sada, Premita Ari Kusumawati, Fumio Hirano, Shigeto Kobayashi, Kenji Nagasaka, Takahiko Sugihara, Nobuyuki Ono, Takashi Fujimoto, Makio Kusaoi, Naoto Tamura, Yasuyoshi Kusanagi, Kenji Itoh, Takayuki Sumida, Kunihiro Yamagata, Hiroshi Hashimoto, Hirofumi Makino, Yoshihiro Arimura, Masayoshi Harigai, Naoyuki Tsuchiya
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
ANCA-associated vasculitis (AAV)
MPO-ANCA
HLA-class II
relapse
genetics
polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1119064/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1119064/full

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