Understanding the self-assembly dynamics of A/T absent 'four-way DNA junctions with sticky ends' at altered physiological conditions through molecular dynamics simulations.

Understanding the self-assembly dynamics of A/T absent 'four-way DNA junctions with sticky ends' at altered physiological conditions through molecular dynamics simulations.

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Elucidation of structure and dynamics of alternative higher-order structures of DNA such as in branched form could be targeted for therapeutics designing. Herein, we are reporting the intrinsically dynamic and folds transitions of an unusual DNA junction with sequence d(CGGCGGCCGC)4 which self-assem...

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Bibliographic Details
Main Authors: Akanksha Singh, Ramesh Kumar Yadav, Ali Shati, Nitin Kumar Kamboj, Hesham Hasssan, Shiv Bharadwaj, Rashmi Rana, Umesh Yadava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0278755

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https://doi.org/10.1371/journal.pone.0278755

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