Selection of a Multidrug Resistance Plasmid by Sublethal Levels of Antibiotics and Heavy Metals

ABSTRACT How sublethal levels of antibiotics and heavy metals select for clinically important multidrug resistance plasmids is largely unknown. Carriage of plasmids generally confers substantial fitness costs, implying that for the plasmid-carrying bacteria to be maintained in the population, the pl...

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Bibliographic Details
Main Authors: Erik Gullberg, Lisa M. Albrecht, Christoffer Karlsson, Linus Sandegren, Dan I. Andersson
Format: Article
Language:English
Published: American Society for Microbiology 2014-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01918-14