Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma

Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma

Abstract Background Chromatin regulators (CRs) are critical epigenetic modifiers and have been reported to play critical roles during the progression of various tumors, but their role in lung adenocarcinoma (LUAD) has not been comprehensively studied. Methods Differential expression and univariate C...

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Bibliographic Details
Main Authors: Yongbiao Huang, Lingyan Xiao, Motuma Yigezu Daba, Duo Xu, Yuan Wang, Long Li, Qian Li, Bo Liu, Wan Qin, Huixian Zhang, Xianglin Yuan
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Clinical Epigenetics
Subjects:
Lung adenocarcinoma
Chromatin regulator
Molecular subtype
Tumor microenvironment
NPAS2
Online Access:https://doi.org/10.1186/s13148-023-01486-w

Internet

https://doi.org/10.1186/s13148-023-01486-w

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