Core genome mediated potential vaccine targets prioritization against Clostridium difficile via reverse vaccinology - an immuno-informatics approach

Core genome mediated potential vaccine targets prioritization against Clostridium difficile via reverse vaccinology - an immuno-informatics approach

The emergence of multi-drug resistance in clostridium difficile is an urgent bio-threat associated with high morbidity and mortality. The availability of core genome sequences for pathogen strains provides the opportunity to rationally approach novel therapeutic targets. No preventive vaccine agains...

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Bibliographic Details
Main Authors: Sara Aiman, Fawad Ali, Asad Zia, Muneeba Aslam, Zhongjie Han, Qurat ul Ain Farooq, Sulaiman Shams, Asifullah Khan, Chunhua Li
Format: Article
Language:English
Published: Aristotle University of Thessaloniki 2022-04-01
Series:Journal of Biological Research - Thessaloniki
Subjects:
clostridium difficile
reverse vaccinology
vaccine candidates
multi-epitopes
chimeric vaccine constructs
Online Access:https://ejournals.lib.auth.gr/jbiolres/article/view/8481

Internet

https://ejournals.lib.auth.gr/jbiolres/article/view/8481

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