miR-16-5p Suppresses Progression and Invasion of Osteosarcoma via Targeting at Smad3

miR-16-5p Suppresses Progression and Invasion of Osteosarcoma via Targeting at Smad3

BackgroundMicroRNAs are known to regulate carcinogenesis of osteosarcoma. Although, miR-16-5p is known to exert inhibitory effects on several forms of cancers, its effects on the growth and invasion of osteosarcoma have not been studied.MethodsWe collected human osteosarcoma specimens and adjacent t...

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Bibliographic Details
Main Authors: Zhijian Gu, Zhikun Li, Ruijun Xu, Xiaodong Zhu, Ruixi Hu, Yonghua Xue, Wei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
osteosarcoma
miR-16-5p
invasion
Smad3
proliferation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01324/full

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