Safety of beta-blocker and calcium channel blocker antihypertensive drugs in pregnancy: a Mendelian randomization study

Safety of beta-blocker and calcium channel blocker antihypertensive drugs in pregnancy: a Mendelian randomization study

Abstract Background Beta-blocker (BB) and calcium channel blocker (CCB) antihypertensive drugs are commonly used in pregnancy. However, data on their relative impact on maternal and foetal outcomes are limited. We leveraged genetic variants mimicking BB and CCB antihypertensive drugs to investigate...

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Bibliographic Details
Main Authors: Maddalena Ardissino, Eric A. W. Slob, Skanda Rajasundaram, Rohin K. Reddy, Benjamin Woolf, Joanna Girling, Mark R. Johnson, Fu Siong Ng, Dipender Gill
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Medicine
Subjects:
Blood pressure
Beta-blocker
Calcium channel blocker
Mendelian randomization
Pregnancy
Online Access:https://doi.org/10.1186/s12916-022-02483-1

Internet

https://doi.org/10.1186/s12916-022-02483-1

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