<it>scribble </it>mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

<p>Abstract</p> <p>Background</p> <p>Metastatic neoplasias are characterized by excessive cell proliferation and disruptions to apico-basal cell polarity and tissue architecture. Understanding how alterations in cell polarity can impact upon tumour development is, there...

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Bibliographic Details
Main Authors: Richardson Helena E, Amin Nancy, Goulding Karen R, Leong Gregory R, Brumby Anthony M
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/7/62