A Survey on the Expression of the Ubiquitin Proteasome System Components HECT- and RBR-E3 Ubiquitin Ligases and E2 Ubiquitin-Conjugating and E1 Ubiquitin-Activating Enzymes during Human Brain Development

A Survey on the Expression of the Ubiquitin Proteasome System Components HECT- and RBR-E3 Ubiquitin Ligases and E2 Ubiquitin-Conjugating and E1 Ubiquitin-Activating Enzymes during Human Brain Development

Human brain development involves a tightly regulated sequence of events that starts shortly after conception and continues up to adolescence. Before birth, neurogenesis occurs, implying an extensive differentiation process, sustained by changes in the gene expression profile alongside proteome remod...

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Bibliographic Details
Main Authors: Stefano Magnati, Eugenio Alladio, Enrico Bracco
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
brain development
neurodevelopmental disorders
neurodegenerative disorders
ubiquitin proteasome system (UPS)
proteome remodeling
machine learning and model classification
Online Access:https://www.mdpi.com/1422-0067/25/4/2361

Internet

https://www.mdpi.com/1422-0067/25/4/2361

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